Explosive-Bomb

of the phenyl ring (which is why its a phenethylamine instead of an
amphetamine), and I *assume* the B is because of the Br atom in the 4
position.
+--------- the second (beta - carbon)
|
v


CH3O /\\ / \ NH2
\ / \\ / \ /
|| |
|| |
|| | ^
/ \ // \ |
Br \// OCH3 +------------ the first (alpha - carbon)


Doses are 12-24mg, Duration is 4-8 hours. Doses of 100mg have been taken
safely. 2C-B seems to be an extraordinarily colorful hallucingen similar
to LSD -- apparently somewhat analytical and dissasociative in higher doses
or in those sensitive to those effects.

Quote from Ecstasy: The MDMA Story...

[begins with a quotation from Alexander Shulgin]:

2C-B... is a tool... which ties the mental processes directly
and constructively into the physical soma.
The analgesic effects experienced with many, if not most,
psychedelic drugs, are not present with 2C-B. On the
contrary, there is increased body awareness of every kind,
including skin sensitivity, heightened responsiveness to
smells, tastes, and sexual stimulation.
One experiences increased consciousness of physical
health and energy, or, on the other hand, sharpened
awareness of any body imbalance or discomfort.
2C-B allows for rich visual imagery and intesnse eyes-
closed fantasy without the cluttering up of the mental field
with too much elaboration... It is a superb tool for learning
and growth.

[...] At high doses (above 30 mgs.), 2C-B is intensely hallucinogenic,
and, like any major psychedelic, can be frightening for certain people.
In small doses, it becomes a mild sensory enhancer but does not have the
strongly empathogenic qualities that MDMA has.
Perhaps the best use that has been found for 2C-B is as a synergist
with MDMA. When taken together, the MDMA pushes the non-specific 2C-B
reaction in a more warm and emphathetic direction. Because 2C-B is a
psychedelic drug, and therefore not fully predictable, its action can take
the user in many different directions. But if the set and setting are right,
2C-B can enhance the desire for sexual orgasm during an MDMA experience.
The synergy of the two substances can on occasion be a true aphrodisiac.

Shulgin writes in PiHKAL:

"The most succesfful reports have followed a program in which the two drugs
are not used at the same time, nor even too closely spaced. It appears that
the optimum time for the 2C-B is at, or just before, the final baseline
recovery of the MDMA."

DOB: 2,5-Dimethoxy-4-Bromoamphetamine. The only chemical difference is
the addition of an extra carbon to the chain. This turns the
phenethylamine into an alpha-methyl-phenethylamine (because the
addition of a carbon means attatching a methyl group to the
alpha carbon of the phenethylamine) also called a phenylisopropylamine
or simply an amphetamine.


CH3O /\\ / \ NH2
\ / \\ / \ /
|| | |
|| | |
|| | CH3
/ \ // \
Br \// OCH3

DOB has a potency of 1.0-3.0 mg and duration of 18-30 hours. Its very
similar to LSD. It seems to be more colorful than LSD and less dissociative
than 2C-B based on the reports I've read. The index of safety is probably
something like over 1,000 times the effective dose.

2C-D (LE-25): 2,5-Dimethoxy-4-Methylphenethylamine. This is the 2 carbon
homologue of DOM (2C-B is to DOB as 2C-D is to DOM). The difference
between 2C-D and 2C-B is simply the replacement of the Br atom with
a methyl group.

CH3O /\\ / \ NH2
\ / \\ / \ /
|| |
|| |
|| |
/ \ // \
H3C \// OCH3

2C-D has a potency of 20-60mg and a duration of 4-6 hours. Seems to also
be very colorful. Shulgin notes: "Wow! This particular compound is what
I call a pharmacological tofu. It doesn't seem to do much by itself, always
teasing, until you get to heroic levels. But a goodly number of experimental
therapists have said that it is excellent in extending the action of some
other materials. It seems to boost the waning action of another drug, without
adding its own color to the experience." At 150mg+ it appears it might be
a full blown 2C-B-like psychedelic, however. No info on the toxic dose.

DOM (STP): 2,5-Dimethoxy-4-Methylamphetamine. Again, simply the addition
of an extra carbon to the chain to turn the phenethylamine 2C-D into
the ampehtamine DOM. And the replacement of the Br atom in DOB with
a methyl group would give you DOM also.


CH3O /\\ / \ NH2
\ / \\ / \ /
|| | |
|| | |
|| | CH3
/ \ // \
H3C \// OCH3

DOM has a potency of about 3-10mg and a duration of 14-20 hours. This was
first synthesized by Shulgin, and is what he calls his "Problem Child" (in
reference to Albert Hofmann's name for LSD). It gained a considerable
amount of use in the 60's and people taking 30mg+ (a whopping dose) had
some very dissasociative, bad trips. It was known as STP, which stands for
the motor oil additive actually, but was also known as "Serenity,
Tranquility and Peace". From the descriptions it seems LSD-like, with
possibly even more of a head-trip. 5-10mg seems *much* more appropriate
from the descriptions with very good effects. Only at higher (20-30mg)
doses does it appear to get really nasty.

And for chemical comparison, MDA and MDMA: 3,4-methylenedioxyamphetamine and
3,4-methylenedioxymethamphetamine respectively... They're somewhat similar
to DOM and DOB -- all the ring substituents need to be knocked off and
replaced with the 3,4-methylenedioxy ring. Then for MDMA you've got the
addition of a methyl group to the nitrogen amine.

MDA:

O /\\ / \ NH2
/ \ / \\ / \ /
/ || | |
H2C || | |
\ || | CH3
\ / \ //
O \//

MDMA:

O /\\ / \ NHCH3
/ \ / \\ / \ /
/ || | |
H2C || | |
\ || | CH3
\ / \ //
O \//

Also we might as well throw in amphetamine if you all haven't figured out
what that should look like yet (replace the NH2 with NHCH3 to get
methamphetamine -- identical substitution as between MDA and MDMA).
Also, if you knock off the CH2 from amphetamine, you'll get phenethylamine
which is the prototype chemical for all the drugs I've listed so far, although
itself its inactive.

amphetamine:

/\\ / \ NH2
/ \\ / \ /
|| | |
|| | |
|| | CH3
\ //
\//

And just for kicks here we have good old LSD which looks nothing like all
these other chemicals:

/ C2H5
H. CON
'. / \ C2H5
/ \
/ \
|| |
|| N
/\\ /\ / \
/ \\ / \ / CH3
|| | | \
|| | | H
\ // \ /
\// \/
| ||
| ||
HN-------

Hope you enjoyed that. Chem dweebs please check to make sure I got
everything correct. I didn't have time to go over this with a fine-toothed
comb.